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Anti -Cytokeratin 6 Rabbit pAb

货号:GB111247

品牌:Servicebio

价格:¥650

规格: 100μl

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Product Information

 

Description

Cytokeratin 6 rabbit polyclonal

Protein full name
Keratin, type II cytoskeletal 6A
 

Synonyms

Cytokeratin-6A, CK-6A, Keratin-6-alpha, mK6-alpha, Keratin-6A, K6A, Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6

Immunogen

Recombinant protein corresponding to Mouse Cytokeratin 6

Isotype IgG
Purity Affinity purification
Subcellular location
 
Cytoplasm
 

Predicted MW.

59 kDa

Observed MW.

59 kDa

Uniprot ID

P02538, P50446, Q4FZU

 


 

Applications

 

Applications

WB

IHC IF
Species

Human, Mouse


Human, Mouse, Rat
 
Human,Mouse, Rat
Dilution

1: 500-1: 1000

1: 1000-1: 2000 1: 1000-1: 2000
Positive tissue

skin

tonsils, skin, stomach skin, stomach

 


 

Background

 

The protein encoded by this gene is a member of the keratin gene family. The Krt6 belongs to type II cytokeratins and consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita.


 

Images

 

Western blot analysis of CK6 (GB111247) at dilution of 1: 1000
Lane 1: A431 cell lysate
Lane 2: Mouse skin tissue lysate

   

Immunohistochemistry analysis of paraffin-embedded human tonsil using CK6 (GB111247) at dilution of 1: 1000

 
   

Immunohistochemistry analysis of paraffin-embedded mouse skin using CK6 (GB111247) at dilution of 1: 1000

 
   

Immunohistochemistry analysis of paraffin-embedded rat skin using CK6 (GB111247) at dilution of 1: 1000
 
   

Immunohistochemistry analysis of paraffin-embedded rat stomach using CK6 (GB111247) at dilution of 1: 1000
 
   

Immunofluorescent analysis of paraformaldehyde-fixed mouse skin using CK6 (GB111247) at dilution of 1: 1000
 
   

Immunofluorescent analysis of paraformaldehyde-fixed rat stomach using CK6 (GB111247) at dilution of 1: 1000
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE:This product is intended for research only.