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Anti -Cyclin D3/CCND3 Rabbit pAb

货号:GB111250

品牌:Servicebio

价格:¥650

规格: 100μl

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Product Information

 

Description

Cyclin D3 rabbit polyclonal

Protein full name
G1/S-specific cyclin-D3
 

Synonyms

Ccnd3, Cyl-3, CyclinD3, D3 type cyclin, G1 S specific cyclin D3

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D3

Isotype IgG
Purity Affinity purification

Predicted MW.

32 kDa

Observed MW.

32 kDa

Uniprot ID

P30281, P30282, P4896

 


 

Applications

 

Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

liver, kidney

 


 

Background

 

Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.


 

Images

 

Western blot analysis of Cyclin D3 (GB111250) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: K562 cell lysate
Lane 3: Jurkat cell lysate
Lane 4: Mouse liver tissue lysate
Lane 5: Mouse kidney tissue lysate
Lane 6: Rat liver tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.